021-51111890
购物车（）
sales@molnova.cn
MDL 100907
CAS No. 139290-65-6
MDL 100907 ( MDL-100907;MDL100907;Volinanserin )
产品货号. M11635 CAS No. 139290-65-6
A potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥664 | 有现货 |
|
| 10MG | ￥1029 | 有现货 |
|
| 25MG | ￥1993 | 有现货 |
|
| 50MG | ￥2568 | 有现货 |
|
| 200MG | ￥5621 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称MDL 100907
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors.
-
产品描述A potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors; demonstrates a clozapine-like profile of potential antipsychotic activity with low extrapyramidal sid-effect liability, and has a superior CNS safety index.Sleep Disorder Phase 3 Discontinued
-
同义词MDL-100907;MDL100907;Volinanserin
-
通路Endocrinology/Hormones
-
靶点5-HT Receptor
-
受体5-HT Receptor
-
研究领域Neurological Disease
-
适应症Sleep Disorder
化学信息
-
CAS Number139290-65-6
-
分子量373.46
-
分子式C22H28FNO3
-
纯度>98% (HPLC)
-
溶解度DMSO: 100 mg/mL (267.8 mM); Ethanol: 18 mg/mL (48.2 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESO[C@@H](C1=CC=CC(OC)=C1OC)C2CCN(CCC3=CC=C(F)C=C3)CC2
-
化学全称(R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Ardayfio PA, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):891-7.
2. Sorensen SM, et al. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91.
3. Kehne JH, et al. J Pharmacol Exp Ther. 1996 May;277(2):968-81.
2. Sorensen SM, et al. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91.
3. Kehne JH, et al. J Pharmacol Exp Ther. 1996 May;277(2):968-81.
产品手册
关联产品
-
5-HT4 antagonist 1
5-HT4 antagonist 1 is an antagonist of 5-HT4 (pKi = 9.6).
-
SB-258585
SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM.
-
WAY-100635 maleate (...
WAY-100635 is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
