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MDL 100907
CAS No. 139290-65-6
MDL 100907 ( MDL-100907;MDL100907;Volinanserin )
产品货号. M11635 CAS No. 139290-65-6
A potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥664 | 有现货 |
|
| 10MG | ￥1029 | 有现货 |
|
| 25MG | ￥1993 | 有现货 |
|
| 50MG | ￥2568 | 有现货 |
|
| 200MG | ￥5621 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称MDL 100907
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors.
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产品描述A potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors; demonstrates a clozapine-like profile of potential antipsychotic activity with low extrapyramidal sid-effect liability, and has a superior CNS safety index.Sleep Disorder Phase 3 Discontinued
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同义词MDL-100907;MDL100907;Volinanserin
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域Neurological Disease
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适应症Sleep Disorder
化学信息
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CAS Number139290-65-6
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分子量373.46
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分子式C22H28FNO3
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纯度>98% (HPLC)
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溶解度DMSO: 100 mg/mL (267.8 mM); Ethanol: 18 mg/mL (48.2 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO[C@@H](C1=CC=CC(OC)=C1OC)C2CCN(CCC3=CC=C(F)C=C3)CC2
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化学全称(R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Ardayfio PA, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):891-7.
2. Sorensen SM, et al. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91.
3. Kehne JH, et al. J Pharmacol Exp Ther. 1996 May;277(2):968-81.
2. Sorensen SM, et al. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91.
3. Kehne JH, et al. J Pharmacol Exp Ther. 1996 May;277(2):968-81.
产品手册
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